J94.0
Conditions
Interventions
Group 1: Children who, following cardiac surgery, develop milky effusion in the pleural drains or continue to present with pleural effusion after five days.
Study Flow: Study Initiation (Inclusion)
•
Sponsors
Kinderkardiologie Uniklinik Erlangen
Eligibility
Sex/Gender
All
Age
No minimum to 18 Years
Inclusion criteria
Inclusion criteria: • Age under 18 years • Pediatric patients in the neonatal, infant, childhood, or adolescent period • Cardiac surgical procedure • Admission to the pediatric intensive care unit after a cardiac surgery performed to correct a congenital or acquired heart defect • Cutoff point: occurrence of a milky chylothorax or persistent pleural effusion = 5 days postoperatively • Radiologically or sonographically confirmed pleural effusion that persists on or beyond the fifth postoperative day • Laboratory confirmation of chylothorax • Evidence by at least one of the following criteria: – Triglyceride concentration in pleural fluid > 110 mg/dL (1.24 mmol/L) – Lymphocyte predominance in the pleural effusion (>70%)
Exclusion criteria
Exclusion criteria: Children who did not develop a chylothorax
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| identification of early biomarkers that can reliably predict the prognosis of chylothorax within the first 72 hours after diagnosis | — |
Countries
Germany
Contacts
Public ContactSven Dittrich
Kinderkardiologie
Outcome results
None listed