E10
Conditions
Interventions
Group 1: After receiving the study documents, participants provide a small blood sample on a card once, complete a questionnaire, and return both in the prepaid envelope.
Sponsors
DiogenX
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Signed and dated informed consent Using insulin to manage T1D. Short period of insulin independence in conjunction with honeymoon period is permissible, based on PI discretion. Willingness and ability to perform at-home DBS sampling after a regular meal and note glucose level at the time of DBS sampling
Exclusion criteria
Exclusion criteria: Any other type of diabetes, apart from T1D. Concomitant participation in an interventional clinical trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postprandial C-peptide concentration (pmol/L) measured from dried blood spot samples collected at home by participants approximately 90 minutes after start of consumption of a regular, self-chosen meal. | — |
Secondary
| Measure | Time frame |
|---|---|
| Proportion of participants who successfully complete the DBS collection and return a valid sample (i.e. sufficient sample quality and completeness for C-peptide analysis). Associations between C-peptide concentration and clinical/demographic variables, including: age, time since diagnosis, BMI, insulin use, and available measures of glycemic control | — |
Countries
Germany
Contacts
Public ContactTheresa Herbrand
Profil Institut für Stoffwechselforschung GmbH
Outcome results
None listed