Periodontitis stage III and IV
Conditions
Interventions
Group 1: Scaling & Rootplaning (SRP) using ultrasconic scaler and Gracey curettes
Group 2: SRP + subgingival trehalose powder air-polishing (TPAP) for 20 seconds per tooth
Group 3: SRP + TPAP + applic
Sponsors
Klinik für Zahnerhaltung, Parodontologie u. Präventive Zahnheilkunde, Universitätsklinikum Aachen
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: • Patients with generalized Stage III or IV periodontitis • At least 18 remaining teeth • At least one single-rooted tooth in each quadrant with at least one site showing a probing depth of = 6 mm (“index tooth”) • Radiographic evidence of periodontal bone loss exceeding 33% of the root length
Exclusion criteria
Exclusion criteria: • Subgingival root surface instrumentation within the last 12 months • Use of local or systemic antibiotics within the last 4 month • Intake of medications associated with the development of gingival overgrowth • Intake of medications affecting bone metabolism (antiresorptives) • Systemic diseases known to interact with periodontal diseases or requiring prophylactic antibiotic coverage • General health risk due to an increased risk of bacteremia • Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change of pocket probing depth (PD), clinical attachment level (CAL) and bleeding on probing (BOP), measured 3 and 6 months after therapy compared to baseline using a pressure-calibrated periodontal probe | — |
Secondary
| Measure | Time frame |
|---|---|
| Differentiation of primary outcome parameters (PD, CAL, BOP) with regard to initial pocket probing depths (PD 4-5mm, PD = 6 mm) and number of closed pockets (pocket closure; PD = 4 mm without BOP) 3 and 6 months after therapy | — |
Countries
Germany, Romania, Switzerland
Contacts
Public ContactJamal M. Stein
Klinik für Zahnerhaltung, Parodontologie u. Präventive Zahnheilkunde
Outcome results
None listed