Indirect neurophysiological measurements of locus coeruleus activity for the study of consciousness and different levels of attention, with its implication in neuromodulation techniques.
Conditions
Interventions
Group 1: Healthy people between 20 and 30 years old. Non-interventional study:
– Pupillometric examinations with an eye tracker (Eyelink 1000, Version 1.5.2).
– Electroenchpalografic examinations (EE
Sponsors
Universitätsklinik für Neurologie
Eligibility
Sex/Gender
All
Age
20 Years to 30 Years
Inclusion criteria
Inclusion criteria: - Healthy participants. - German or English as a first or second language. - Age between 20 and 30 years.
Exclusion criteria
Exclusion criteria: – Acute or past iritis – Previous neurological or psychiatric conditions. – Relevant eye diseases (including previous eye surgery, glaucoma, pseudoexfoliation syndrome at the pupillary margin or lens, corneal diseases, non-spheroidal pupils, relevant anisocoria), diabetes mellitus. – Use of centrally acting medications according to Table 2 of Kelbsch et al. (2019). – Multifocal contact lenses, mirrored lenses, or glasses with a lot of shiny jewelry (provided these can be removed and visual acuity is sufficient to focus on the fixation cross, participants can of course be included, and the measurement will be performed without visual aids).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pupillary responses in healthy participants between 20 and 30 years old. | — |
Secondary
| Measure | Time frame |
|---|---|
| Electroencephalographic responses in healthy participants between 20 and 30 years old. | — |
Countries
Germany
Contacts
Public ContactKarsten Witt
Universitätsklinik für Neurologie
Outcome results
None listed