Patients with breast cancer risk genes, rare genetic disorders, lupus erythematosus, vitiligo, Hashimoto's thyroiditis, patients taking kinase inhibitors
Conditions
Interventions
Group 1: Patient groups suspected of having genetic or autoimmune diseases that could cause increased sensitivity to radiation are studied for these conditions.
Sponsors
Strahlenklinik
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with genetic variants suspected of inducing increased radiation sensitivity. Patients with autoimmune diseases suspected of inducing increased radiation sensitivity. Patients with tumors and taking kinase inhibitors.
Exclusion criteria
Exclusion criteria: Patients < 18 years of age, with the exception of: Genetic background of the germ line in childhood tumors. Children with Fanconi anemia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Identification of radiation-sensitive cohorts by measuring chromosomal aberrations. | — |
Secondary
| Measure | Time frame |
|---|---|
| Identification of clinical characteristics indicating increased radiation sensitivity | — |
Countries
Austria, Denmark, Germany, Norway, Switzerland
Contacts
Public ContactLuitpold Distel
Strahlenklinik
Outcome results
None listed