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Prospective clinical cohort study to investigate wound healing in patients with osteoporosis receiving antiresorptive therapy with bisphosphonates after tooth extractions, based on a comparison of bacterial adhesion to two types of suture material.

Prospective clinical cohort study to investigate wound healing in patients with osteoporosis receiving antiresorptive therapy with bisphosphonates after tooth extractions, based on a comparison of bacterial adhesion to two types of suture material. - MRONJ

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00037740
Enrollment
24
Registered
2025-10-06
Start date
2023-08-01
Completion date
Unknown
Last updated
2025-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K10.2

Interventions

Group 1: Monofilamente sutures for wound closure after dentoalveolar tooth extractions, which are removed again after wound healing is complete (10 days later) and examined for bacterial adhesion Grou

Sponsors

Mund-Kiefer-und Gesichtschirurgie
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: • Postmenopausal patients suffering from osteoporosis • Patients undergoing treatment with antiresorptive drugs, including bisphosphonates used to treat osteoporosis • Patients requiring dental extraction therapy

Exclusion criteria

Exclusion criteria: • Patients who have other diseases in addition to osteoporosis • Patients who have already been treated with radiation in the head and neck area or are being treated at the time of surgery • Patients with diseases that interfere with wound healing (e.g., diabetes mellitus, HIV infection, treatment with immunosuppressants)

Design outcomes

Primary

MeasureTime frame
To what extent wound care with monofilament suture materials results in better wound healing and less bacterial adhesion than with multifilament absorbable materials.

Secondary

MeasureTime frame
The secondary endpoints are the correlation of EHS with this bacterial adhesion and the evaluation of the clinical parameters collected as a correlation to this. In addition, the correlation with the preoperative smear and bacterial colonization should be analyzed here.

Countries

Germany

Contacts

Public ContactMayte Buchbender

Mund-Kiefer- und Gesichtschirurgie

maytebuchbender@gmail.com+4991318533614

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026