Vagal modulation through breathing exercises: An intervention study in patients with rheumatoid arthritis

Vagal modulation through breathing exercises: An intervention study in patients with rheumatoid arthritis - Breath-RA

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00037733

Enrollment

Registered

2025-08-20

Start date

2025-09-01

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

M06

Interventions

Group 1: Intervention group: Breathing sessions: The individual breathing sessions are led by a certified yoga teacher and doctor. The sessions are conducted by the applicant herself. In addition, fil

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with rheumatoid arthritis, confirmed by ACR/EULAR criteria (2010), stable disease activity, written informed consent.

Exclusion criteria

Exclusion criteria: Pregnancy, bradycardia, severe cardiac arrhythmias, severe psychiatric disorders

Design outcomes

Primary

Measure	Time frame
Investigation of the effect of respiratory therapy on HRV in RA patients at the beginning and after 8 weeks - Investigation of the effect of respiratory therapy on lung function using spirometry at the beginning and after 8 weeks in RA patients - Measurement of inflammatory activity using laboratory parameters (e.g., CRP, leukocytes) after respiratory therapy at the beginning and after 8 weeks in patients with RA - Investigation of the effect of respiratory therapy on blood pressure at the beginning and after 8 weeks in RA patients - Investigation of the effect of respiratory therapy on subjective stress perception using PSQ (Perceived Stress Questionnaire) in RA patients at the beginning and after 8 weeks - Investigation of the effect of respiratory therapy on fatigue using FACIT and on depressive moods using BDI in RA patients at the beginning and after 8 weeks - Investigation of the effect of respiratory therapy on quality of life using SF-36 in RA patients at the beginning and after 8 weeks - Investigation of the effect of respiratory therapy on the use of NSAIDs (non-steroidal anti-inflammatory drugs) using a specially developed questionnaire in RA patients at the beginning and after 8 weeks - Investigation of the effect of respiratory therapy on subjective sleep quality using PSQI (Pittsburgh Sleep Quality Index) in RA patients at the beginning and after 8 weeks	—

Measure

Time frame

Investigation of the effect of respiratory therapy on HRV in RA patients at the beginning and after 8 weeks - Investigation of the effect of respiratory therapy on lung function using spirometry at the beginning and after 8 weeks in RA patients - Measurement of inflammatory activity using laboratory parameters (e.g., CRP, leukocytes) after respiratory therapy at the beginning and after 8 weeks in patients with RA - Investigation of the effect of respiratory therapy on blood pressure at the beginning and after 8 weeks in RA patients - Investigation of the effect of respiratory therapy on subjective stress perception using PSQ (Perceived Stress Questionnaire) in RA patients at the beginning and after 8 weeks - Investigation of the effect of respiratory therapy on fatigue using FACIT and on depressive moods using BDI in RA patients at the beginning and after 8 weeks - Investigation of the effect of respiratory therapy on quality of life using SF-36 in RA patients at the beginning and after 8 weeks - Investigation of the effect of respiratory therapy on the use of NSAIDs (non-steroidal anti-inflammatory drugs) using a specially developed questionnaire in RA patients at the beginning and after 8 weeks - Investigation of the effect of respiratory therapy on subjective sleep quality using PSQI (Pittsburgh Sleep Quality Index) in RA patients at the beginning and after 8 weeks

—

Secondary

Measure	Time frame
- Examination of the intervention and control groups for group-specific differences at the beginning and after 8 weeks - Examination of compliance and acceptance of respiratory therapy in RA patients at the beginning and after 8 weeks	—

Countries

Germany

Contacts

Public ContactHarriet Morf

Uniklinik Erlangen

harriet.morf@uk-erlangen.de+4991318543023

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026