Quantifying the risk of caesarean sections on a uterine rupture in pregnant women between 24 and 42 weeks` gestation undergoing a planned or unplanned caesarean section – a retrospective, single centre case-control study in a tertiary care facility

Quantifying the risk of caesarean sections on a uterine rupture in pregnant women between 24 and 42 weeks` gestation undergoing a planned or unplanned caesarean section – a retrospective, single centre case-control study in a tertiary care facility - QUantification of the risk of A uterine Rupture depending on the number of prior C-sections (QUARC)

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00037706

Enrollment

1800

Registered

2025-10-01

Start date

2025-05-05

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

O71.0

Interventions

Group 1: No uterine rupture patients for the control group from 2010 to 2025, considering given matching criteria. Group 2: Cases with a uterine rupture between the years 2010 and 2025.

Eligibility

Sex/Gender

Female

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Women with a singleton pregnancy aged 18 and above who meet the criteria of a planned or unplanned caesarean section with at least 1 prior c-section in their medical history will be recruited. They will be between 23+0- and 42+0-weeks’ gestation.

Exclusion criteria

Exclusion criteria: Patients will be ineligible to be included if they have a history of maternal congenital uterine malformations or critical illnesses that may not allow them to make autonomous decisions. A potential participant is ineligible if there is doubt that the individual was able to understand the circumstances, express a preference or act freely. An individual is also deemed ineligible on those grounds if a health care proxy is involved.

Design outcomes

Primary

Measure	Time frame
Quantifying the risk of prior c-sections associated with a uterine rupture during pregnancy	—

Secondary

Measure	Time frame
Estimating blood loss during surgery depending on the number of prior c-sections	—

Countries

Germany

Contacts

Public ContactFelix Borgmeier

Universitätsfrauenklinik

felix.borgmeier@med.uni-duesseldorf.de+492118107599

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026