L20.9
Conditions
Interventions
Group 1: Intervention Group: Specific Bioactive Collagen Peptides (BCP)
Description:
Participants (n = 15) receive a daily dose of 5 g of specific bioactive collagen peptides (bovine origin, average
Sponsors
CRI Collagen Research Institute GmbH
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Diagnosed atopic dermatitis 2. SCORAD (SCOring Atopic Dermatitis) 15-40 3. Written informed consent
Exclusion criteria
Exclusion criteria: 1. Other acute skin diseases (e.g., psoriasis, urticaria, parasitic infections such as mites, scabies, lice, or fleas) 2. Other dermatological findings (e.g., scars, sunburn, moles) 3. intensive natural or artificial UV exposure (e.g., solarium) 4. Food allergies or intolerances to any ingredients of the test products 5. Gastrointestinal diseases or digestive disorders 6. Tattoos in the test areas 7. Use of topical medications on the test areas within 6 weeks prior to study start 8. Systemic use of anti-inflammatory agents or antibiotics within 2 weeks prior to study start 9. Pregnancy or breastfeeding 10. Immunological disorders 11. Severe health problems within the last 6 months (e.g., cancer, acute cardiovascular disorders, severe diabetes) 12. Alcohol or drug abuse 13. Participation in other studies involving cosmetic products applied to the test areas within 2 weeks prior to or during the study 14. Participation in a pharmaceutical study within 4 weeks prior to study start 15. Intake of nutritional supplements within 4 weeks prior to or during the study 16. Significant changes in lifestyle or eating habits during the study 17. Use of leave-on products or oily skin cleansing products on the arms 18. Intellectual or mental impairments preventing compliance with study instructions
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in pruritus intensity, measured by the 5-D Pruritus Scale from baseline to week 12. Change in SCORAD score (overall atopic dermatitis severity) from baseline to week 12. Change in transepidermal water loss (TEWL) in lesional and non-lesional skin. Change in skin hydration (Corneometer® measurement) in lesional and non-lesional skin. Change in skin pH in lesional and non-lesional skin. Amount of topical corticosteroid rescue medication used during the study. | — |
Secondary
| Measure | Time frame |
|---|---|
| Amount of emollient/body lotion used during the study. | — |
Countries
Germany
Contacts
Public ContactSteffen Oesser
CRI Collagen Research Institute GmbH
Outcome results
None listed