The Regenokine Registry: An open, real-world database investigating the incidence, safety and efficacy of cell-free autologous conditioned serum (ACS) in the treatment of pain conditions. A project of the Orthogen Study Group (OSG) and the Research Network of Autologous Conditioned Serum users, carried out in cooperation with the Canadian Research Chair in Human Pain Genetics and other corporate partners

The Regenokine Registry: An open, real-world database investigating the incidence, safety and efficacy of cell-free autologous conditioned serum (ACS) in the treatment of pain conditions. A project of the Orthogen Study Group (OSG) and the Research Network of Autologous Conditioned Serum users, carried out in cooperation with the Canadian Research Chair in Human Pain Genetics and other corporate partners - OrthoRegReg

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00037691

Enrollment

1000

Registered

2026-04-20

Start date

2026-05-15

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain conditions

Interventions

Group 1: This research project is not a study in itself, but rather a process of collecting data as part of creating a registry. No additional measures or examinations will be carried out beyond thos

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1) Confirmed pain condition or sensory disorder; 2) Ongoing or incipient routine administration of cell-free ACS alone or in combination; 3) Minimum 18 years old; 4) Sufficient ability to communicate in national language of the respective country, German or English language; 5) Patient must be able to recognize the nature, significance and scope of this registry and to act accordingly; 6) Given declaration of consent.

Exclusion criteria

Exclusion criteria: none

Design outcomes

Primary

Measure	Time frame
This register serves exclusively as a data collection for future research projects in which hypotheses based on this data are to be tested. Within the scope of these projects, evaluation criteria, expected effects, and influencing factors will then be defined. The following topics are recorded in the registry: - Organizational information; - Sociodemographic characteristics; - Medical history (reasons for seeking treatment, extent of pain, etc.); - Pain, joy of life, and general activity scale (PEG); - Medication intake; - Current therapy; - General questions (e.g., general complaints, operations, hospital stays, etc.); - Clinical assessment (indication-specific); - Quality of life (QOL) assessment; - Safety; - Reason for termination, change, or premature discontinuation of treatment.	—

Measure

Time frame

This register serves exclusively as a data collection for future research projects in which hypotheses based on this data are to be tested. Within the scope of these projects, evaluation criteria, expected effects, and influencing factors will then be defined. The following topics are recorded in the registry: - Organizational information; - Sociodemographic characteristics; - Medical history (reasons for seeking treatment, extent of pain, etc.); - Pain, joy of life, and general activity scale (PEG); - Medication intake; - Current therapy; - General questions (e.g., general complaints, operations, hospital stays, etc.); - Clinical assessment (indication-specific); - Quality of life (QOL) assessment; - Safety; - Reason for termination, change, or premature discontinuation of treatment.

—

Countries

Germany

Contacts

Public ContactJana Wehling

Gemeinschaftspraxis Dr. Wehling & Partner Regenerative Orthopädie und Schmerzmedizin

team@doctor-wehling.com+49 211 38700 12

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: May 1, 2026