Metabolic signatures of T cells in polyomavirus-associated nephropathy (PyVAN): comparison of immunosuppressive drugs and adaptation strategies

Metabolic signatures of T cells in polyomavirus-associated nephropathy (PyVAN): comparison of immunosuppressive drugs and adaptation strategies - TIMES-PyVAN

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00037669

Enrollment

176

Registered

2025-08-13

Start date

2025-10-01

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

B34.4 Z94.0

Interventions

Group 1: Kidney transplant patients with BK viremia: Patients and healthy volunteers who meet the inclusion criteria are offered participation in the study by their attending physician during an outpa

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Have had a kidney transplant or are planning to have a kidney transplant from a living donor - Do not have hepatitis B/C and/or HIV

Exclusion criteria

Exclusion criteria: - Minor age - Lack of capacity to consent - Viral infections such as hepatitis B, hepatitis C, and/or HIV - Pregnancy

Design outcomes

Primary

Measure	Time frame
Number of virus-specific T cells	—

Secondary

Measure	Time frame
Graft failure	—

Countries

Germany

Contacts

Public ContactOliver Witzke

Universitätsklinikum Essen AöR

oliver.witzke@uk-essen.de+492017230

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 14, 2026