cardiorespiratory and inflammatory health endpoints
Conditions
Interventions
Group 1: Changes in health parameters in healthy participants depending on whether they cycled along low-traffic versus high-traffic routes and the associated differences in air pollution exposure in
Sponsors
Heinrich-Heine-Universität Düsseldorf, Institut für Medizinische Soziologie, Center for Health and Society (chs)
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Healthy adults aged 18 to 65 years will be included. Due to active participation in road traffic, participants should be experienced cyclists.
Exclusion criteria
Exclusion criteria: Insufficient basic knowledge of German, as communication may be necessary during the rides; existing or planned pregnancy; active smoking; daily passive smoking; occupational or recreational exposure to high levels of fine dust; existing unstable cardiovascular diseases; lung diseases; diabetes; chronic infectious diseases; thyroid disorders; neurological or mental illnesses; as well as conditions that prevent participation in spirometry.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| All health examinations will be conducted immediately before and immediately after the cycling tours. A predefined sequence of health examinations will be followed on all examination days. The cycling tours will always start at 8:30 a.m. The health examinations for the participants will take place from 7:00–8:15 a.m. and from 10:00–11:15 a.m. Cardiovascular assessments: pulse wave analysis, pulse wave velocity, heart rate variability, blood pressure Lung function assessments: spirometry Inflammation: FeNO test | — |
Secondary
| Measure | Time frame |
|---|---|
| Air pollution exposure: PNC 10–300 nm [#/cm³]; Nitrogen dioxide (NO2) [ppb]; Wind; Meteorology; GPS | — |
Countries
Germany
Contacts
Public ContactClaudia Pischke
Institut für Medizinische Soziologie
Outcome results
None listed