acute renal failure
Conditions
Interventions
Group 1: Hemodialysis with a cytokine-eliminating hemodialysis membrane
Sponsors
Universitätsklinik Würzburg
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: Requiring hemodialysis for renal replacement therapy; end-stage oder acute renal failure requiring dialysis; current acute bacterial oder viral infection, such as pneumonia, urinary tract infection etc.; presence of blood access for routine hemodialysis (AV fistula or catheter); ability to give consent for participation in the study; presence of the patient's written informed consent.
Exclusion criteria
Exclusion criteria: Women being pregnant or breast feeding; risk of bleeding resulting from comorbidity or recent surgery; known allergy to components of the extracorporeal therapy; existence of contraindications for the administration of heparin for anticoagulation including heparin-induced thrombocytopenia type II; existence of morbidities with assumed life expectancy below 6 months; circulatory instability.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Removal of low-molecular weight proteins and cytokines from blood | — |
Secondary
| Measure | Time frame |
|---|---|
| Loss of albumin into dialysate; occurrence of dialysis-associated side effects | — |
Countries
Germany
Contacts
Public ContactChristoph Wanner
Universitätsklinik Würzburg
Outcome results
None listed