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Effect of yogurt consumption on periodontal inflammation in patients with periodontitis- a randomized controlled trial

Effect of yogurt consumption on periodontal inflammation in patients with periodontitis- a randomized controlled trial - JOPARI

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00037586
Enrollment
40
Registered
2025-11-05
Start date
2026-02-06
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K05.3

Interventions

Group 1: Test group: yoghurt consumption 2 x 150 g per day for 60 days Group 2: Control group: no additional yogurt consumption over 60 days

Sponsors

Poliklinik für Zahnerhaltung, Bereich Parodontologie
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Adults =18 years of age - Generalized periodontitis stage 3 grades B-C - At least 10 own teeth - BOP = 40 % - Signed informed consent

Exclusion criteria

Exclusion criteria: - Severe general diseases (e.g. infections, malignant tumors) - Antibiotics taken 6 weeks before the start of the study - Taking medication that can change the bleeding or inflammatory behavior of the gums (e.g. anticoagulants, steroids, NSAIR) - Pregnancy, breastfeeding - Women of childbearing potential without contraception - Lactose intolerance - Already high consumption of natural yoghurt - Unwillingness to abstain from yoghurt consumption during the study with the exception of the yoghurt consumption specified by the study - Smoking > 10 cig/day (equivalent to other tobacco products) - Planned dental treatments (e.g. prophylaxis, periodontitis treatment, prosthetic restorations) - Simultaneous participation in other clinical trials (up to 4 weeks before the start of the study)

Design outcomes

Primary

MeasureTime frame
Difference in bleeding on probing (BOP) after 60 days of yogurt consumption compared to the control group without yogurt intake.

Secondary

MeasureTime frame
Clinical attachment level (CAL), probing depths (ST), furcation involvement, tooth mobility, plaque index, gingival index: difference between baseline and 60 days compared to the control group.

Countries

Germany

Contacts

Public ContactJohan Wölber

Poliklinik für Zahnerhaltung, Bereich Parodontologie

johan.woelber@ukdd.de+49 351 4582712

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Apr 4, 2026