Overactive Bladder
Conditions
Interventions
Group 1: Female patients with urgency or mixed urinary incontinence who, at the time of data collection, had undergone conservative pharmacological treatment and had not received any botulinum toxin t
Sponsors
Uniklinik RWTH Aachen
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: female, = 18 years, diagnosed with urge incontinence or mixed incontinence, has undergone urodynamic testing, has received pharmacological therapy and/or botulinum toxin injections into the bladder
Exclusion criteria
Exclusion criteria: Known urological pre-existing conditions such as bladder carcinoma, urethral stricture, bladder stones; spinal cord syndrome
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urodynamic parameters: first desire to void (ml), maximum desire to void (ml), bladder capacity (ml), post-void residual volume (ml), presence of detrusor instability (yes/no), result of the stress test (positive/negative). ? The primary endpoint is the comparison of the above-mentioned pre-therapeutic urodynamic parameters between patients who respond to a standardized conservative first-line therapy and those who subsequently received botulinum toxin. These parameters are collected as part of guideline-based diagnostic evaluation using urodynamic testing at the time of diagnosis and are therefore usually obtained shortly after the patients’ initial presentation to our urogynecological outpatient clinic. | — |
Secondary
| Measure | Time frame |
|---|---|
| Time interval between therapy initiation and therapy change (delay due to unsuccessful conservative treatment) Correlation of clinical parameters (age, BMI, parity, comorbidities, etc.) with therapy response | — |
Countries
Germany
Contacts
Public ContactKaroline Eisfeld
Uniklinik RWTH Aachen
Outcome results
None listed