Degeneration of the spine (e.g., herniated disc, spinal canal stenosis, spondylolisthesis), vertebral infection (e.g., spondylitis, spondylodiscitis, facet joint arthritis), and osteoporotic vertebral/pelvic fracture.
Conditions
Interventions
Group 1: Patients with (suspected) underlying degeneration of the spine (e.g., herniated disc, spinal canal stenosis, spondylolisthesis), vertebral infection (e.g., spondylitis, spondylodiscitis, face
Sponsors
Universitätsklinikum Bonn
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: • Suspicion of a degenerative, inflammatory disease or osteoporotic fracture of the spine or pelvic skeleton • The patient is able to understand the nature, significance, and implications of the decision to participate in the study and to act in accordance with their wishes. • A declaration of consent dated and signed by the patient is available.
Exclusion criteria
Exclusion criteria: Lack of consent to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difficult to specify when collecting biomaterials. With the consent of the patients and the ethics committee, the materials are to be stored for 20 years for various different investigations. Duration for individual patients: From inclusion in the study/admission to routine discharge from inpatient treatment, clinical follow-up examination during routine check-ups if necessary. This involves the collection of blood samples and intraoperative samples and the recording of clinical findings, e.g., using the Oswestry Disability Index. | — |
Secondary
| Measure | Time frame |
|---|---|
| The aim is to build up a collection of tissue samples (intraoperative biomaterial, e.g. from intervertebral discs) and corresponding blood samples over a period of 10-20 years and to investigate various microbiological and immunological questions using different methods. | — |
Countries
Germany
Contacts
Public ContactLioba Bürvenich
Universitätsklinikum Bonn Klinik und Poliklinik für Orthopädie und Unfallchirurgie
Outcome results
None listed