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Efficacy, tolerability, and adherence to ketogenic diet therapy in children and adults with epilepsy

Efficacy, tolerability, and adherence to ketogenic diet therapy in children and adults with epilepsy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00037551
Enrollment
40
Registered
2025-08-12
Start date
2025-10-15
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G40

Interventions

Group 1: Children and adults with epilepsy who are treated with ketogenic diet therapy
a retrospective chart review will be performed based on data available in the hospital information system/patient files, examining changes in seizure frequency one year after therapy initiation or at

Sponsors

Universitätsmedizin Frankfurt am Main
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Diagnosis of epilepsy, treatment with ketogenic diet therapy

Exclusion criteria

Exclusion criteria: Lack of relevant clinical or therapeutic information

Design outcomes

Primary

MeasureTime frame
The primary outcome is the change in seizure frequency one year after the start of ketogenic dietary therapy or at the end of therapy. The target variable is the seizure frequency in the last month before the one-year mark or before discontinuation of therapy. This is compared to the seizure frequency in the month prior to the start of therapy. The primary endpoint is determined based on information collected during routine clinical examinations from the patient or their relatives/caregivers.

Secondary

MeasureTime frame
Occurrence of adverse effects Influence of clinical, therapeutic, and psychosocial variables (epilepsy syndrome, age, gender, duration of epilepsy, severity, KET form, psychosocial resources)

Countries

Germany

Contacts

Public ContactJohann Philipp Zöllner

Universitätsmedizin Frankfurt am Main

zoellner@med.uni-frankfurt.de06963017466

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 7, 2026