C61
Conditions
Interventions
Group 1: Representation of differentially expressed genes depending on metastasis status and progression speed, identification of the tumor microenvironment, and development of multimodal prediction m
Sponsors
LMU Klinikum
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Prostate Cancer (ISUP 2 to 4) - Prostatectomy at LMU University Hospital
Exclusion criteria
Exclusion criteria: - Lymph node metastases or hematogenous metastases at first diagnosis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Representation of differentially expressed genes and pathways between primary tumors of metastatic and non-metastatic patients. | — |
Secondary
| Measure | Time frame |
|---|---|
| - Visualization of differentially expressed genes and pathways between fast and slow progressing patients - Identification of prostate cancer–specific tumor microenvironment subtypes (TCGA) and validation in spatial transcriptomic profiles of metastatic and non-metastatic patients - Development of multimodal predictive models for metastasis risk and progression velocity | — |
Countries
Germany
Contacts
Public ContactChristian Trapp
LMU Klinikum
Outcome results
None listed