K90.0
Conditions
Interventions
Group 1: Group A: Patients with newly diagnosed celiac disease
haven't started gluten free diet yet
Group 2: Group B: Patients who have already been diagnosed with celiac disease
started gluten free diet 3 months ago (10-16 weeks)
Group 3: Group C: Patients who have already been diagnosed with celiac disease
started gluten free diet at least 1 year ago
Group 4: Group D: Age- and gender-matched patients from the pediatric and adolescent gastroenterology consultation without celiac disease
Group 5: Group E:
Sponsors
St. Josef-Hospital
Eligibility
Sex/Gender
All
Age
3 Years to 17 Years
Inclusion criteria
Inclusion criteria: • Group A: newly diagnosed celiac disease in accordance with guidelines while consuming a gluten-containing diet (histological and/or serological) • Group B: celiac disease diagnosed in accordance with guidelines and strict gluten-free diet for 3 months (10–16 weeks) • Group C: Celiac disease diagnosed in accordance with guidelines and strict gluten-free diet for at least 12 months • Group E: Maximum age difference between siblings of 3 years
Exclusion criteria
Exclusion criteria: • Lack of consent from legal guardians and patients • Lack of language comprehension • Age under 3 years • Other accompanying chronic inflammatory bowel diseases • Diabetes mellitus type I/II • Psoriasis • Fructose malabsorption • Other concomitant diseases requiring long-term medication • Parenteral nutrition • Group A: gluten-free diet already started before inclusion in the study • Groups D and E: diagnosed celiac disease or indication of existing celiac disease, gluten-free diet
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nutrient profile based on a 7-day food and symptom diary using a nutritional calculation program (GastroSmart, Berlin, Germany) before and after initiation of a GFD, energy content of food, amount of fiber consumed, amount of soluble and insoluble fiber | — |
Secondary
| Measure | Time frame |
|---|---|
| Recording of somatic parameters (height, weight, BMI, head circumference, upper arm circumference, triceps skinfold thickness, Z-values, percentiles, BIA, Tanner stage), Recording of clinical symptoms (intestinal symptoms and stool habits), Laboratory parameters, Bone parameters, Movement protocol (MoMo-AFB), Quality-of-life questionnaire (KIDSCREEN-27 Index), Social status (MacArthur Scale) | — |
Countries
Germany
Contacts
Public ContactAnjona Schmidt-Choudhury
Universitätsklinik für Kinder- und Jugendmedizin, St. Josef-Hospital, Bochum
Outcome results
None listed