Multi-channel transcranial current stimulation (mc-tCS): a novel approach to modulate smooth pursuit eye movement control in healthy individuals and patients with psychotic disorders

Multi-channel transcranial current stimulation (mc-tCS): a novel approach to modulate smooth pursuit eye movement control in healthy individuals and patients with psychotic disorders - mc-TCS

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00037405

Enrollment

Registered

2025-07-17

Start date

2025-08-01

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F20-F29 F30.2 F31.2 F31.5 F32.3 F33.3

Interventions

Group 1: Healthy participants - Magnetic Resonance Imaging (MRI) and Electroencephalography (EEG) during slow eye pursuit movements for the identification of structural and functional brain networks -

Eligibility

Sex/Gender

All

Age

18 Years to 55 Years

Inclusion criteria

Inclusion criteria: - IQ above 70 - sufficient visual acuity (0.8 – 1.0) - fluent German language - written informed consent for participation in the study - Psychosis patients: schizophrenia or schizoaffective disorder according to ICD-10 criteria

Exclusion criteria

Exclusion criteria: - substance abuse during the last three months or lifetime substance dependence - intake of sedative or other medication with known oculomotor effects 48 hours prior to testing (benzodiazepines, carbamazepine) - history of severe head trauma or brain damage including stroke, tumor, epilepsy

Design outcomes

Primary

Measure	Time frame
Study objective: Correlative and Causal Investigation of Sensorimotor Neural Networks During Slow Eye Pursuit Movements	—

Secondary

Measure	Time frame
Secondary objectives: (1) Exploratory analysis of structural and functional sensorimotor neural networks during pursuit eye movements in healthy subjects and psychosis patients (2) Assessment of the impact of repeated personalized transcranial electrical stimulation on SP eye movements in healthy subjects and psychosis patients (3) Assessment of the impact of repeated personalized transcranial electrical stimulation on electrophysiological correlates of eye movements in healthy subjects and psychosis patients (4) Assessment of the impact of repeated personalized transcranial electrical stimulation on cognitive performance in psychosis patients - See study protocol for details	—

Measure

Time frame

Secondary objectives: (1) Exploratory analysis of structural and functional sensorimotor neural networks during pursuit eye movements in healthy subjects and psychosis patients (2) Assessment of the impact of repeated personalized transcranial electrical stimulation on SP eye movements in healthy subjects and psychosis patients (3) Assessment of the impact of repeated personalized transcranial electrical stimulation on electrophysiological correlates of eye movements in healthy subjects and psychosis patients (4) Assessment of the impact of repeated personalized transcranial electrical stimulation on cognitive performance in psychosis patients - See study protocol for details

—

Countries

Germany

Contacts

Public ContactRebekka Lencer

Universität zu Lübeck, Klinik für Psychiatrie und Psychotherapie

rebekka.lencer@uni-luebeck.de+49 451 500 73895

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 14, 2026