Immune competence as well as disease progression, treatment response, and complications in patients with various diseases, particularly in oncology and cardiology, but not limited to these.
Conditions
Interventions
Group 1: Observational Study:
Arm 1:
Analysis of CT/MRI imaging and routine clinical data (body structures/ organs, body composition, diagnoses, laboratory values, clinical outcomes) without any addit
Sponsors
Universitätsklinikum Frankfurt am Main
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Presence of a clinically indicated CT or MRI examination including imaging of the thorax and/or abdomen or a cardiac CT. For the prospective validation arm additionally: existing venous access and capacity to provide informed consent.
Exclusion criteria
Exclusion criteria: Objection to the use of clinical routine data, missing or incomplete imaging data. For the prospective validation arm additionally: lack of capacity to provide informed consent, no venous access.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Development and validation of an interpretable imaging-based immune score based on routine CT/MRI data for the non-invasive assessment of individual immune competence and its correlation with clinical outcomes as well as biological immune parameters. | — |
Countries
Germany
Contacts
Public ContactSimon Bernatz
Universitätsklinikum Frankfurt am Main
Outcome results
None listed