Investigation of the immunological response in healthy adults following the consumption of decaffeinated coffee in comparison to caffeinated coffee.
Conditions
Interventions
Group 1: Participants undergo a 5-day washout phase prior to the intervention.
On the evening before the intervention day, participants receive a standardized meal.
The following morning, they arrive
Sponsors
Core Facility Human Studies, ZIEL - Institute for Food and Health, Technische Universität München
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: males and females BMI between 18.5 and 24.9 kg/m2 aged between 18 and 40
Exclusion criteria
Exclusion criteria: Current tobacco consumption Deviation from normal weight (BMI 24.9 kg/m2) Practice of competitive sports (>10h/week) Known metabolic disorders, lipid metabolism disorders, diabetes mellitus or untreated thyroid dysfunction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Caffeine level after coffee consumption and control IL-6 level in the blood IL-6/IL-10 quotient | — |
Secondary
| Measure | Time frame |
|---|---|
| Haplotype of the bitter receptor TAS2R38 IL-1 receptor antagonist level Correct identification of the sensory abnormal sample Subjective sensation of bitterness | — |
Countries
Germany
Contacts
Public ContactThomas Skurk
Core Facility Human Studie, ZIEL - Institute for Food and Health, Technische Universität München
Outcome results
None listed