Non-interventional study on different treatment modalities in first permanent molars affected by molar incisor hypomineralization (MIH)

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00037326

Enrollment

250

Registered

2025-10-06

Start date

2025-11-01

Completion date

Unknown

Last updated

2025-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Molar-Incisor-Hypomineralisation (MIH), Enamel hypomineralisation

Interventions

Group 1: Monitoring Group 2: Pit and fissure sealing/ composite material Group 3: Pit and fissure sealing/ GIC material Group 4: Minimal-invasive coverage of enamel breakdowns/ composite material Grou

Eligibility

Sex/Gender

All

Age

5 Years to 18 Years

Inclusion criteria

Inclusion criteria: MIH-related dental intervention indicated on at least one first permanent molar

Exclusion criteria

Exclusion criteria: No MIH

Design outcomes

Primary

Measure	Time frame
Survival of the tooth, the dental pulp and the provided interventions over 3 years (after 1 week, 3, 6, 12, 24 und 36 months)	—

Secondary

Measure	Time frame
Survival of MIH-related opacities	—

Countries

Germany

Contacts

Public ContactJan Kühnisch

Poliklinik für Zahnerhaltung, Parodontologie und Digitale Zahnmedizin

jan.kuehnisch@med.uni-muenchen.de+4989440059343

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026