Hybrid-NOTES versus conventional laparoscopic cholecystectomy: A retrospective and prospective single-center study comparing long-term surgical outcomes and patient satisfaction

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00037312

Enrollment

500

Registered

2025-11-05

Start date

2025-09-15

Completion date

Unknown

Last updated

2025-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

female patients after cholecystectomy

Interventions

Group 1: Hybrid transvaginal NOTES cholecystectomy Group 2: laparoscopic cholecystectomy

Eligibility

Sex/Gender

Female

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Minimum age of 18 years - Radiologically and clinically confirmed indication for cholecystectomy - For the hybrid-NOTES cholecystectomy cohort, preoperative gynecological evaluation completed

Exclusion criteria

Exclusion criteria: - age < 18 Jahre

Design outcomes

Primary

Measure	Time frame
Patient satisfaction and quality of life will be prospectively assessed using the SF-36 questionnaire during the follow-up period (1 to 9 years) after hybrid NOTES or laparoscopic cholecystectomy.	—

Secondary

Measure	Time frame
- Sexual function (PISQ-12) - Body image and self-perception (BIS score) - Postoperative complications - Operative time and length of hospital stay - 30-day readmission rate all questionnaires are assessed once in the period 1 to 9 years after either hybrid NOTES or laparoscopic cholecystectomy	—

Countries

Germany

Contacts

Public ContactCarsten Kamphues

Park-Klinik Weißensee

Carsten.Kamphues@parkkliniken.de+49 30 96283552

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026