Retrospective validation of sCD40 as a prognostic biomarker for postoperative pancreas-specific complications in PDAC patients

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00037293

Enrollment

185

Registered

2025-07-02

Start date

2017-12-17

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

POPF/PPH in PDAC patients

Interventions

Group 1: Retrospective analysis of all PDAC patients who underwent oncological resection of the pancreatic head as a pylorus-preserving pancreatoduodenectomy (PPPD) or Whipple procedure between 2017 a

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: PDAC patients, who underwent surgical treatment in the form of a pylorus-preserving pancreatoduodenectomy (PPPD) or a Whipple procedure.

Exclusion criteria

Exclusion criteria: Total pancreatectomy or distal pancreatectomy.

Design outcomes

Primary

Measure	Time frame
Determination of sCD40 serum levels in preoperative serum samples of PDAC patients who underwent a PPPD or Whipple procedure between 2017 and 2022, and correlation with the occurrence of postoperative pancreas-associated complications.	—

Countries

Germany

Contacts

Public ContactLena Seifert

Klinik für Viszeral-, Thorax- und Gefäßchirurgie; Universitätsklinikum Carl Gustav Carus Dresden

lena.seifert@ukdd.de0351-45816398

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026