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Intensive Language-Action Therapy combined with Acceptance and Commitment Therapy for group-based transdisciplinary treatment of post-stroke depression and aphasia (SYNERGY)

Intensive Language-Action Therapy combined with Acceptance and Commitment Therapy for group-based transdisciplinary treatment of post-stroke depression and aphasia (SYNERGY) - SYNERGY I

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00037284
Enrollment
1
Registered
2025-07-23
Start date
2025-07-29
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F06.3

Interventions

Group 1: MIT combined with ACT
3-week waiting period followed by 3-week intensive intervention phase
frequency: 3 sessions per week, each lasting 2.5 hours per day (2 hours of MIT, 0.5 hours of ACT)

Sponsors

Medical School Berlin
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: - left-hemispheric cortical or subcortical ischemic or hemorrhagic event - stroke occurred at least 6 months prior to study enrolment - German as first native language - right-handedness, as confirmed by the Oldfield Handedness Inventory - diagnosis of aphasia with at least basic auditory verbal comprehension skills, as confirmed by the Aachen Aphasia Test

Exclusion criteria

Exclusion criteria: - other severe neurological disorders - significant uncorrectable visual or hearing disability - severe nonverbal cognitive deficits, as revealed by the Corsi Block-Tapping Task - simultaneous speech-language therapy or psychotherapy during the 3-week intervention phase

Design outcomes

Primary

MeasureTime frame
Feasibility, defined as at least 80% attendance rate during the intervention phase

Secondary

MeasureTime frame
(1) Symptoms of depression, assessed with the simplified version of the Beck Depression Inventory (BDI-V) and the Hamilton Rating Scale for Depression (HAM-D) (2) Verbal expression skills, assessed with the word repetition subscale of the Aachen Aphasia Test (AAT)

Countries

Germany

Contacts

Public ContactBenjamin Stahl

Medical School Berlin

benjamin.stahl@medicalschool-berlin.de030 7668 375 600

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 14, 2026