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Evaluation of Retrospective Samples for Tropical Medicine Diagnostic Assays

Evaluation of Retrospective Samples for Tropical Medicine Diagnostic Assays - EVAREST

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00037274
Enrollment
1760
Registered
2025-07-17
Start date
2025-12-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ICD-10, see below B65 B78 A06 B74.9 B66.3 B53 B55 B66.4

Interventions

Group 1: stored sera collected from individuals tested for schistosomiasis, strongyloidiasis, amoebiasis, filariasis, fascioliasis, malaria, leishmaniasis and paragonimiasis at the Department for Infe

Sponsors

Universitätsklinikum Heidelberg, Abteilungen für Infektions- und Tropenmedizin, Parasitologie
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: - Sera of patients known to be positive for schistosomiasis, strongyloidiasis, amoebiasis, filariasis, fascioliasis, malaria, leishmaniasis or paragonimiasis - Serological control group sera of patients known to be negative for respective pathogens

Exclusion criteria

Exclusion criteria: • No specific exclusion criteria

Design outcomes

Primary

MeasureTime frame
1.1 Determine diagnostic accuracy of commercial serological tests for schistosomiasis, strongyloidiasis, amoebiasis, filariasis, fascioliasis, malaria, leishmaniasis or paragonimiasis using microscopy and molecular assays as reference standard 1.2. Determine diagnostic accuracy of commercial serological tests for schistosomiasis, strongyloidiasis, amoebiasis, filariasis, fascioliasis, malaria, leishmaniasis or paragonimiasis using microbiological tests as reference standard and in-house serology as comparator

Secondary

MeasureTime frame
2.1 evaluate PCRs on serum of patients known to be infected for schistosomiasis for diagnostic accuracy 2.2 evaluate PCRs on serum of patients known to be infected and treated for schistosomiasis for changes from baseline during treatment

Countries

Germany

Contacts

Public ContactClaudia Denkinger

Universitätsklinikum Heidelberg

claudia.denkinger@uni-heidelberg.de+4962215622999

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 10, 2026