C50
Conditions
Interventions
Group 1: Participants with an increased risk of breast and ovarian cancer who have presented at the Center for Familial Breast and Ovarian Cancer at the University Hospital Düsseldorf over the past 20
Sponsors
Klinik für Frauenheilkunde und Geburtshilfe, Universitätsklinikum Düsseldorf
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. BRCA1/2 mutation carriers at the FBREK Center Düsseldorf from 2004–2023, regardless of disease status. 2. Consent for re-contact for clinical studies has been given. 3. Consent to participate in the prospective questionnaire study.
Exclusion criteria
Exclusion criteria: Patients with high-risk mutations who do not meet the inclusion criteria listed above and/or who presented at the FBREK Center Düsseldorf outside the period 2004–2023.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Determination of the rate of risk-reducing mastectomies in the cohort of BRCA1/2 mutation carriers at the FBREK Center of the University Women’s Hospital Düsseldorf, in relation to factors that may influence their decision-making regarding participation in the intensified early detection program versus opting for risk-reducing mastectomy. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome is the evaluation of the subjective satisfaction of BRCA1/2 mutation carriers with the counseling they have received regarding intensified early detection versus risk-reducing mastectomy. These data will be prospectively collected by means of the questionnaire. | — |
Countries
Germany
Contacts
Public ContactNadia Stamm
Klinik für Frauenheilkunde und Geburtshilfe
Outcome results
None listed