E83.0
Conditions
Interventions
Group 1: Patients with confirmed Wilson's disease who were treated at the study center in the period 2010-2025.
Group 2: Patients with other hepatological diseases who were treated at the study center
Sponsors
Universitätsklinikum Heidelberg
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients of any age with a confirmed diagnosis of Wilson's disease (Leipzig Score >4 points). Patients of any age in whom the presence of Wilson's disease was suspected but not confirmed (Leipzig Score <4 points). Patients of any age with other hepatological diseases in an appropriate number (usually 2:1 to the Wilson's disease group in individual questions) as a comparison group.
Exclusion criteria
Exclusion criteria: none
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Retrospective comparison of the results of laboratory, histologic, radiologic and genetic diagnostics between Wilson's disease patients and patients with other hepatologic diseases. | — |
Secondary
| Measure | Time frame |
|---|---|
| Identification of independent risk factors for a severe course (neurological manifestation, death, liver transplantation, hepatic decompensation). Identification of new biochemical markers for personalized therapy management. | — |
Countries
Germany
Contacts
Public ContactIsabelle Mohr
Universitätsklinikum Heidelberg
Outcome results
None listed