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The influence of the severity of tricuspid valve insufficiency and right ventricular function on the correlation between non-invasive (echocardiography) and invasive (right heart catheterization) measurements of systolic pulmonary artery pressure (SPAP).

The influence of the severity of tricuspid valve insufficiency and right ventricular function on the correlation between non-invasive (echocardiography) and invasive (right heart catheterization) measurements of systolic pulmonary artery pressure (SPAP).

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00037159
Enrollment
584
Registered
2025-06-25
Start date
2025-07-01
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

tricuspid valve regurgitation, systolic pulmonary artery pressure, systolic right ventricular function

Interventions

Group 1: A single group of patients is being studied retrospectively, with each patient having undergone both transthoracic echocardiography (TTE) and right heart catheterization (RHC). Patients must

Sponsors

Klinikum Bayreuth
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: • Performance of transthoracic echocardiography (TTE) and right heart catheterization (RHC) during the same inpatient stay • Presence of tricuspid valve regurgitation • Maximum interval of 7 days between TTE and RHC • Adequate assessability of all relevant echocardiographic and invasive hemodynamic (RHC) parameters with valid measurements • Comprehensive transthoracic echocardiography • The recruitment period was defined as the period between September 19, 2017, and January 21, 2025

Exclusion criteria

Exclusion criteria: • Patients under 18 years of age • Absence of tricuspid valve Regurgitation • Intervall more than 7 days between the echocardiography and the right heart catheterization (RHC) • Inadequate assessment of echocardiographic or invasive hemodynamic (as part of RHC) measurement parameters (SPAP) • Incomplete echocardiographic examination or documentation (inferior vena cava diameter, TAPSE, etc.)

Design outcomes

Primary

MeasureTime frame
1. The correlation between invasive (using right heart catheterization) and non-invasive (using transthoracic echocardiography) measurements of systolic pulmonary artery pressure (SPAP), depending on the severity of tricuspid valve regurgitation (TR), divided into mild, moderate, and severe categories. 2. The influence of right ventricular function (evaluated by TAPSE =Tricuspid Annular Plane Systolic Excursion) on the correlation between invasively and non-invasively measured SPAP.—

Secondary

MeasureTime frame
A subgroup analysis to differentiate between precapillary and postcapillary pulmonary hypertension (PH) concerning the concordance of invasively and noninvasively determined SPAP values.—

Countries

Germany

Contacts

Public ContactTaki Eddine Sid

Klinikum Bayreuth

TakiEddine.Sid@klinikum-bayreuth.de0921 4006502

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026