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Open-label Placebo – acceptability and expected effectiveness of different forms of administration

Open-label Placebo – acceptability and expected effectiveness of different forms of administration

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00037111
Enrollment
350
Registered
2025-07-18
Start date
2025-08-06
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypothetically imagined tension headache (vignette-based scenario)

Interventions

Group 1: Control Group, treatment vignette conventional medication Sociodemographic information, current health status, and medication use are assessed first. All participants then read the same init
Devilly & Borkovec, 2000). This serves to capture baseline expectations and the perceived plausibility independently of the treatment content. Participants then read a treatment vignette in which a c
Richmond et al., 2022) 2. German modified Health Anxiety Inventory (MK-HAI
Bailer & Witthöft, 2006) 3. General Self-Efficacy Scale (SWE
Jerusalem & Schwarzer, 1999) 4. A people-pleasing scale developed by us In addition, four general items assessing belief in the effectiveness of placebos are presented. Finally, participants are aske

Sponsors

Universität Graz
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: good knowledge of German

Exclusion criteria

Exclusion criteria: no participation in the pilot study

Design outcomes

Primary

MeasureTime frame
Expectation and credibility ratings are assessed twice via the Credibility/Expectancy Questionnaire (CEQ; Devilly & Borkovec, 2000), once after the presentation of the case vignette and once after the presentation of the treatment vignette. Perceived appropriateness of the treatment and self-reported willingness to use the treatment are measured using two items following the treatment vignette. The analysis is based on the vignette study by Haas et al. (2021).

Secondary

MeasureTime frame
The associations between various predictor variables (e.g., health anxiety, trust in physicians, type of treatment, etc.) and the personal treatment acceptability will be examined.

Countries

Austria, Germany, Switzerland

Contacts

Public ContactAnne Schienle

Universität Graz

anne.schienle@uni-graz.at+43 (0)316 380 - 5086

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Apr 4, 2026