Gender-Specific Differences in the Management of Patients with Obesity Hypoventilation Syndrome (OHS) Receiving Non-Invasive Ventilation (NIV) – A Retrospective Single-Center Data Analysis

Gender-Specific Differences in the Management of Patients with Obesity Hypoventilation Syndrome (OHS) Receiving Non-Invasive Ventilation (NIV) – A Retrospective Single-Center Data Analysis - GENOHS-NIV

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00037099

Enrollment

Registered

2025-06-03

Start date

2025-06-16

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

E66.2

Interventions

Group 1: Retrospective Analysis • Collection of demographic and clinical baseline data • Analysis of capillary blood gas values • Evaluation of extracted NIV device data • Assessment of quality of lif

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: • Patients with a confirmed diagnosis of OHS • Chronic respiratory failure type II with established NIV therapy • Ongoing NIV therapy for a minimum duration of 3 months • Complete data sets available in the hospital’s documentation system CCP/KISS

Exclusion criteria

Exclusion criteria: • Age < 18 years • Lack of capacity to provide informed consent • Incomplete or missing data sets in the CCP/KISS documentation system • Patients with a primary neurological or pulmonary underlying disease as the main cause of respiratory failure (e.g., COPD, pulmonary fibrosis, neuromuscular diseases)

Design outcomes

Secondary

Measure	Time frame
• Gender-specific analysis of quality of life using the Severe Respiratory Insufficiency Questionnaire (SRI) • Comparison of gender-specific therapy adherence and compliance	—

Primary

Measure	Time frame
Gender-specific comparison of clinical outcomes following the initiation of NIV therapy with regard to: • Duration of NIV use • Device settings • Capillary blood gas analysis (pCO2, pO2, pH)	—

Countries

Germany

Contacts

Public ContactSarah Bettina Stanzel

Kliniken der Stadt Köln, Klinik für Pneumologie, Beatmungsmedizin und thorakale Onkologie

stanzels@kliniken-koeln.de+49 221-890718337

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026