Retrospective analysis of radiation treatment plans for patients with meningiomas, acoustic neuromas or other benign neoplasms in the brain

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00037040

Enrollment

3000

Registered

2025-06-11

Start date

2024-08-20

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

D32 D33.3 D35.2

Interventions

Group 1: Patients who have undergone radiotherapy, either as adjuvant or definitive treatment, for meningiomas, acoustic neuromas, or other benign neoplasms located in the brain are included in this s

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: ? Definitive or postoperative percutaneous radiotherapy ? Radiotherapeutic treatment of a benign neoplasm in the brain

Exclusion criteria

Exclusion criteria: Age < 18 years

Design outcomes

Primary

Measure	Time frame
The primary objective is to analyze the extent of the radiation fields (especially planning target volume (PTV)), compare it among the different patient cases and correlate it with the survival data (e.g. overall survival (OS) or local control (LC)).	—

Secondary

Measure	Time frame
Secondary objectives include the recording of side effects such as the frequency of cerebral edema and radionecrosis and comparison with the dose distribution. To this end, an analysis of the radiation exposure of the organs at risk (e.g. brain, brain stem, optic nerves) and quality control with the corresponding constraints will be carried out. In addition, an analysis of the different irradiation techniques (e.g. 3D plan, VMAT) will be carried out and, in particular, the side effect profiles and the failure rate will be considered.	—

Measure

Time frame

Secondary objectives include the recording of side effects such as the frequency of cerebral edema and radionecrosis and comparison with the dose distribution. To this end, an analysis of the radiation exposure of the organs at risk (e.g. brain, brain stem, optic nerves) and quality control with the corresponding constraints will be carried out. In addition, an analysis of the different irradiation techniques (e.g. 3D plan, VMAT) will be carried out and, in particular, the side effect profiles and the failure rate will be considered.

—

Countries

Germany

Contacts

Public ContactSebastian Maier

LMU Klinikum, Klinik und Poliklinik für Strahlentherapie und Radioonkologie

sebastian.maier@med.lmu.de+49 89 4400 73770

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 10, 2026