isolation of macro- and microcirculation, (tissue) hypoperfusion, formation of edema
Conditions
Interventions
Group 1: healthy term newborns (>36+6 pregnancy weeks)
Hyperspectral imaging of the thorax (= HSI: spectrum, tissue oxygenation (StO2), near infrared perfusion index (NIR), tissue hemoglobin index (TH
Sponsors
Universitätsklinikum Heidelberg, Klinik für Neonatologie
Eligibility
Sex/Gender
All
Age
No minimum to 17 Years
Inclusion criteria
Inclusion criteria: consent of legal guardians
Exclusion criteria
Exclusion criteria: missing consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| There is a difference in microcirculation (perfusion, oxygenation and tissue water content) and rheology between newborns, preterms and older kids, which can be shown by hyperspectral imaging | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in microcirculation by therapeutic interventions (fluid boli, vasopressor therapy, transfusion) can be measured by hyperspectral imaging (fluid/vasopressor responsiveness). To predict the success of therapeutic interventions, AI-based models can be used by analysing microcirculatory changes the a basis of hyperspectral image data. HSI (supported by AI-based models) can be used to predict Sepsis in pediatric patients. | — |
Countries
Germany
Contacts
Public ContactChristian Gille
Universitätsklinikum Heidelberg, Klinik für Neonatologie
Outcome results
None listed