Evaluation of aortic valve stiffness as a novel parameter for aortic stenosis

Evaluation of aortic valve stiffness as a novel parameter for aortic stenosis - AVA-STIFF

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00037000

Enrollment

200

Registered

2025-05-22

Start date

2025-09-08

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I35.0

Interventions

Group 1: Patients with varying degress of aortic stenosis (none to sever) Baseline visit: - evaluation of the aortic valve with transthoracic and transoesophageal echocardiography - 6 minute walking

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Indication for transosophageal echocardiography

Exclusion criteria

Exclusion criteria: - bicuspid aortic valve - existing aortic valve replacement - non-degenerative aortic valve stenosis - contraindications for transosophageal echocardiography - unable to give consent

Design outcomes

Primary

Measure	Time frame
Progress of aortic valve stenosis (aortic valve replacement, hospitalizations, symptoms)	—

Secondary

Measure	Time frame
cardiac stress (left ventricular function, biomarkers)	—

Countries

Germany, Switzerland

Contacts

Public ContactMichael Wester

Universitätsklinikum Regensburg

michael.wester@ukr.de0941-944-7210

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026