J44.9
Conditions
Interventions
Group 1: Collection and implementation of:
1. Medical history and assessment of patient history
2. Handgrip strength measurement
3. BORG scale (degree of dyspnea)
4. mMRC (modified dyspnea scale)
5. S
Sponsors
Kliniken der Stadt Köln, Klinik für Pneumologie, Beatmungsmedizin und thorakale Onkologie
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients with a known diagnosis of COPD (all GOLD stages) and type 2 respiratory failure Adherence to guideline-based pharmacological therapy Consent to the data protection policy and provision of written informed consent Cognitive and linguistic ability to complete the questionnaires
Exclusion criteria
Exclusion criteria: Age < 18 years Patients lacking capacity to give informed consent Rheumatoid arthritis or other chronic inflammatory joint diseases with relevant involvement of the wrists or finger joints Carpal tunnel syndrome or comparable peripheral nerve compression syndromes of the upper extremity Chronic polyneuropathies with sensorimotor involvement of the hands Corticosteroid-induced or primary myopathies Neurological disorders with impaired hand motor function (e.g., Parkinson's disease, status post cerebrovascular insult, amyotrophic lateral sclerosis) Cervical radiculopathies or plexopathies with documented muscle weakness in the dominant hand Musculoskeletal disorders or acute pain syndromes of the hand or forearm (e.g., tenosynovitis, advanced osteoarthritis) Recent injuries, surgeries, or other conditions that may interfere with standardized grip strength testing
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| •Measurement of muscle strength (handgrip strength as an indicator of overall muscle strength) •Assessment of quality of life (standardized questionnaires such as SRI, BORG scale, mMRC) | — |
Secondary
| Measure | Time frame |
|---|---|
| •Comparison of muscle strength with additional lung function parameters (e.g. FEV1, blood gas analysis) •Assessment of handgrip strength in relation to COPD severity •Investigation of the correlation between muscle strength, mobility, and dyspnea (mMRC, SARC-F) | — |
Countries
Germany
Contacts
Public ContactSarah Stanzel
Kliniken der Stadt Köln, Klinik für Pneumologie, Beatmungsmedizin und thorakale Onkologie
Outcome results
None listed