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Dental focus searches and their significance in medicine

Dental focus searches and their significance in medicine

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00036955
Enrollment
566
Registered
2025-05-22
Start date
2025-05-17
Completion date
Unknown
Last updated
2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K08.9

Interventions

Group 1: Patients in whom a dental focus was identified during the dental infection screening. These patients receive appropriate treatment (focus elimination) if indicated. Complete clinical examina

Sponsors

LMU Klinikum
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients who underwent dental infection screening at the Department of Conservative Dentistry and Periodontology at LMU Munich between July 12, 2008, and December 1, 2024. A clear medical indication for the screening, such as before: Radiation or chemotherapy, Anti-resorptive or anti-angiogenic therapy, Organ transplantation, Or systemic inflammatory conditions of unclear origin. Availability of complete clinical and radiological documentation. Unique KAS-ID enabling linkage to clinical outcome data.

Exclusion criteria

Exclusion criteria: Incomplete clinical records (e.g., missing radiographs or periodontal documentation). Unclear or undocumented indication for screening. No possibility for pseudonymized data linkage (e.g., missing KAS-ID). Patients not referred for infection screening in the context of relevant medical therapy.

Design outcomes

Primary

MeasureTime frame
The primary endpoint of the study is the occurrence of therapy-associated complications, specifically: Jaw necrosis (e.g., medication-related or radiation-induced osteonecrosis), Impaired wound healing, Transplant-related complications, potentially linked to the presence of untreated odontogenic infection foci.

Secondary

MeasureTime frame
Secondary Endpoints: Prevalence of odontogenic foci in various underlying conditions or treatment indications, Association between focus treatment and complication prevention, Type and extent of focus management (e.g., extractions, periodontal therapy), Influence of patient-specific factors (e.g., age, underlying disease, medication) on complication risk.

Countries

Germany

Contacts

Public ContactMatthias Fowlaczny

Poliklinik für Zahnerhaltung und Parodontologie

matthias.folwaczny@med.uni-muenchen.de089 4400 59301

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026