magnesium status
Conditions
Interventions
Group 1: 250 mg magnesium per day as magnesiumoxid for 20 weeks
Group 2: 250 mg magnesium per day as magnesiumcitrate for 20 weeks
Group 3: 250 mg magnesium per day as magnesiumoxid /-citrate (80/20)
Sponsors
Hermes Arzneimittel GmbH
Eligibility
Sex/Gender
All
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: Voluntary participation confirmed with signature; young adults between 20 and 40 years old, BMI between 18.5 - 29.9 kg/m²
Exclusion criteria
Exclusion criteria: Phenylketonuria; Excessive alcohol consumption; Any tobacco use or any cannabis consumption; Excessive physical activity (overexercise); Competitive sports; Underweight (BMI < 18.5 kg/m²) and obesity (BMI = 30 kg/m²); Known diagnoses of atrioventricular block (AV Block); Bradyarrhythmias (bradyarrhythmias and conduction blocks); Myasthenia gravis; Severe renal insufficiency; Use of diuretics; Coagulopathy ((blood) coagulation disorder); Hemophobia (blood-injury phobia); (Oral) anticoagulants (use of anticoagulant medication); Regular intake of dietary supplements containing magnesium; (Chronic) use of glucocorticoids; Any diagnosed cardiovascular disease, metabolic disorders, or chronic inflammatory diseases requiring pharmacological treatment; (Food) intolerances to acesulfame, aspartame, xylitol, or other artificial sweeteners or sugar substitutes; Diagnosed gastrointestinal disorders (inflammatory bowel disease [IBD], celiac disease, short bowel syndrome, status post bariatric surgery, etc.); Pregnancy and breastfeeding (nursing)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Magnesium concentration in peripheral blood mononuclear cells (PBMCs) before and after 20 weeks of supplementation | — |
Secondary
| Measure | Time frame |
|---|---|
| Magnesium concentration in erythrocytes, plasma, and 24 h urine. Different gastrointestinal, psychological, muscular, and nervous complaints before and after 20 weeks of supplementation | — |
Countries
Germany
Contacts
Public ContactSandra Habicht
Institut für Ernährungswissenschaft, Justus Liebig Universität
Outcome results
None listed