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The Mandibular Retrusion Appliance (MRA) as a novel treatment for Class III patients

The Mandibular Retrusion Appliance (MRA) as a novel treatment for Class III patients

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
DRKS
Registry ID
DRKS00036817
Enrollment
20
Registered
2025-05-07
Start date
2025-01-10
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Angle Class III malocclusion

Interventions

Group 1: Patients with moderate Class III-malocclusion are treated with MRA

Sponsors

Universitätsklinikum Mainz, Poliklinik für Kieferorthopädie/Kieferorthopädische Praxis Dr. Michael Wagner Saarbrücken
Lead Sponsor

Eligibility

Sex/Gender
All
Age
13 Years to 18 Years

Inclusion criteria

Inclusion criteria: - permanent dentition - little to no residual growth - maximum negative overjet of -2 mm - a mesial bite less than 4 mm from Class I For MARA/MRA patients: -asymmetric occlusion up to 4 mm form Class I per side - midline shifts up to 3 mm

Exclusion criteria

Exclusion criteria: Foreseeable need for surgical intervention (orthognathic surgery, camouflage treatmenr)

Design outcomes

Primary

MeasureTime frame
Clinical therapeutic outcomes of moderate Angle Class III patients after treatment with the novel MRA. Evaluated parameters were: - Achievement of Class I occlusion - Improvement of Overjet - Changes in cephalometric parameters (SNA,SNB, ANB, WITS)

Secondary

MeasureTime frame
Additional therapeutic effects such as: - Correction of asymmetric occlusions (Class II/Class III) with MARA/MRA-combination - Correction of midlineshifts - Patient acceptance, stability and handling of the appliance

Countries

Germany

Contacts

Public ContactChristina Erbe

Universitätsklinikum Mainz, Poliklinik für Kieferorthopädie

erbe@uni-mainz.de06131 17-3024

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 11, 2026