The study should provide valuable insights into the glucose metabolism of athletes. This can be used to make more precise recommendations, for example for glucose administration before competitions or during training. The study results could also provide information on which forms of training are particularly suitable for people with prediabetes/diabetes in order to improve glucose tolerance in the long term. positively influence glucose tolerance in the long term.
Conditions
Interventions
Group 1: Group of trained people who have been exercising for at least six hours a week for at least three years. At least 80% of this must be strength training and 20% may include other forms of trai
Sponsors
Deutsche Sporthochschule Köln
Eligibility
Sex/Gender
All
Age
18 Years to 30 Years
Inclusion criteria
Inclusion criteria: Persons of male, female or diverse gender; age 18-30 years, training volume of endurance training, strength training or combined strength and endurance training of at least six hours/week for at least three hours/week for at least three years. For the groups that primarily do either endurance training or strength training, it is important that at least 80% of their weekly training training workload in the respective primary form of training. The group that combined strength training and endurance training may not exceed a difference of 20% between the two different forms of training. between the two different forms of strength training and endurance training.
Exclusion criteria
Exclusion criteria: Known chronic diseases (diabetes mellitus, hyperlipidemia, high blood pressure, etc. and, if applicable, corresponding medication). corresponding medication). The diseases leading to exclusion include in particular known performance- or training-limiting illnesses of various kinds (cardiovascular diseases, e.g. uncontrollable heart diseases, e.g. uncontrollable cardiac arrhythmia, heart failure (EF < 55), PAOD (Fontaine stage = II), degenerative joint diseases or muscular diseases). Chronic gastrointestinal diseases, as the performance of the oral glucose tolerance test in the side effect profile can cause gastrointestinal problems. The following are also exclusion criteria: Smoking status, acute oncological diseases or a history of such diseases (< 5 years), infections (HIV, hepatitis), addictions, neurological disorders, psychiatric disorders, existing pregnancy. illnesses, existing pregnancy. The use of oral contraceptives (contraceptive pill) or thyroid preparations and painkillers also lead to exclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| After an introductory discussion including information, the subjects are invited to a one-off examination and measurement. The collection of the primary endpoints therefore takes place at the beginning of the study, as it is a one-time data collection after the background research and preparations have been carried out and a positive ethics application has been submitted. The ?-glucose values are determined as primary endpoints. These are obtained by means of an oral glucose tolerance test in which capillary blood samples are taken at the time points t = 0, 30 min, 60 min, 90 min, 120 min. Further primary endpoints are muscle mass, fat-free mass and fat mass, which are determined once by means of a bioelectrical impedance analysis before the oral glucose tolerance test is carried out. Body composition is measured using an 8-electrode bioelectrical impedance analysis (BIA) from Selvas Healthcare. Bioelectrical impedance analysis is used to differentiate the composition of the body. A weak and imperceptible alternating current is passed through the body. This allows the different types of tissue to be detected, as fat, muscle, bone tissue and body water conduct the current differently. Eight electrodes are attached to both hands and feet so that the 8-point bioelectrical impedance analysis guarantees a segmental measurement of the torso, arms and legs. This allows very precise results to be obtained for muscle mass, particularly in the case of asymmetrical muscle mass distribution. | — |
Secondary
| Measure | Time frame |
|---|---|
| Insulin sensitivity and beta cell function (HOMA-ß index) are calculated using the primary endpoints. The hemodynamic variables (blood pressure, pulse wave, peripheral resistance) are determined in an initial examination before the measurements are taken. In addition, the test subjects must provide individual information regarding training intensity, training method, previous illnesses, medication, age and gender, which is determined by means of a questionnaire. | — |
Countries
Germany
Contacts
Public ContactChristian Brinkmann
Abteilung für Präventive und Rehabilitative Sport- und Leistungsmedizin, Institut für Kreislaufforschung und Sportmedizin
Outcome results
None listed