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Clinical evaluation of polymer-infiltrated ceramic network (PICN) material versus zirconia lithium silicate (ZLS) ceramic for the restoration of worn posterior dentitions – A randomized controlled split-mouth trial

Clinical evaluation of polymer-infiltrated ceramic network (PICN) material versus zirconia lithium silicate (ZLS) ceramic for the restoration of worn posterior dentitions – A randomized controlled split-mouth trial - PICN vs ZLS

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
DRKS
Registry ID
DRKS00036795
Enrollment
22
Registered
2026-01-14
Start date
2026-04-29
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Loss of tooth structure

Interventions

Group 1: Polymer-infiltrated ceramic network material (PICN) restorations Group 2: Zirconia lithium silicate restorations

Sponsors

Zentrum für Zahnmedizin
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Informed Consent signed by the subject - Eroded posterior dentition - In need of increasing the vertical dimension = 1 mm (in the premolar region) - In need of minimal 4 posterior restorations (2 per side) in the maxilla and/or mandible

Exclusion criteria

Exclusion criteria: - Women who are pregnant or breast feeding at the date of inclusion - Known or suspected non-compliance, drug or alcohol abuse - Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. of the participant - Diagnosis of active bulimia nervosa or anorexia - Untreated periodontal disease - Teeth in need of a conventional full-crown restoration - Clinical signs of active bruxism

Design outcomes

Primary

MeasureTime frame
As a primary outcome, the success rate of the posterior restorations, based on the ratings of the USPHS criteria, will be compared among the two restorative materials after 5 years of function.

Secondary

MeasureTime frame
Secondary endpoints will be assessed at different time-points: Baseline, 1-year, 3-year and 5-years. • Patient-related outcome measures (PROMs) evaluated with the OHIP-14 questionnaire • Periodontal and clinical parameters • Volumetric analysis of the casts • Success rates, based on the USPHS criteria

Countries

Switzerland

Contacts

Public ContactPune NIne Paque

Zentrum für Zahnmedizin, Klinik für Rekonstruktive Zahnmedizin

punenina.paque@zzm.uzh.ch+41 44 634 04 04

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 10, 2026