Establishment of a spectral tissue library and perfusion imaging using hyperspectral imaging (HSI) in intracranial vascular and neoplastic pathologies

Establishment of a spectral tissue library and perfusion imaging using hyperspectral imaging (HSI) in intracranial vascular and neoplastic pathologies - SPECTRE: Spectral Perfusion and Evaluation of Cerebral Tissue via Reflectance-based Examination

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00036771

Enrollment

200

Registered

2025-05-05

Start date

2024-03-01

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Meningiomas, Gliomas, Brain metastases, Cerebral aneurysms, Arteriovenous malformations, Vestibular schwannoma, Cavernoma

Interventions

Group 1: Intraoperative in-vivo visualization of neoplastic or vascular neurosurgical pathologies using HSI.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Cranial neoplastic or vascular disease

Exclusion criteria

Exclusion criteria: Patients incapable of giving informed consent (lack of voluntary agreement). Pregnant or breastfeeding women, and individuals planning pregnancy (considered particularly vulnerable groups). Children and adolescents under 18 years of age (considered particularly vulnerable population).

Design outcomes

Primary

Measure	Time frame
In-vivo differentiation of pathological and healthy tissue based on spectral signature	—

Secondary

Measure	Time frame
Correlation of HSI parameters with MRI signal intensities Correlation of HSI data with molecular and immunohistochemical markers Correlation of perfusion parameters and oxygenation with neurological outcome	—

Countries

Germany

Contacts

Public ContactJohannes Wach

Klinik und Poliklinik für Neurochirurgie

johannes.wach@medizin.uni-leipzig.de+493419717500

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 27, 2026