Medication-related problems
Conditions
Interventions
Group 1: Hospitalized adult patients at German university hospitals who are (co-)managed by ward-based clinical pharmacists.
Sponsors
Uniklinikum Bonn
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients aged 18 years and older who are treated on wards with ward pharmacists involvement.
Exclusion criteria
Exclusion criteria: - Pediatric wards - Intensive care units (ICUs) - Maternity wards
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary objective of INTERPOLAR-1-BN is to estimate, in a monocentric setting, the mean number of medication-related problems (MRPs) in hospitalized patients (cohort prevalence) as well as the resolution rate of identified MRPs in routine clinical care. The previous approach under "Usual Care" (number of manually documented MRPs) is about to be compared to the intervention phase, which incorporates IT-based support for pharmacists, including algorithmic MRP detection. During the intervention phase, the number of MRPs includes both manually documented MRPs and algorithmically detected MRPs classified as clinically relevant (such as absolute contraindications, identified using the drug-disease list developed within the study). | — |
Secondary
| Measure | Time frame |
|---|---|
| Furthermore, the following secondary evaluation objectives will be pursued: (1) Analysis of the profiles of detected MRPs (contraindications, missing medications, dosing errors, administration errors, adverse drug reactions); (2) Analysis of the profiles of resolved MRPs; (3) Predictability of MRPs (regression models); (4) Assessment of the effort required for the detection and resolution of MRPs in routine clinical care | — |
Countries
Germany
Contacts
Public ContactKatharina Karsten Dafonte
Uniklinikum Bonn
Outcome results
None listed