P28.5 P27.1
Conditions
Interventions
Group 1: Name of group:
Arm 1 – Skin assessment during EIT electrode application (“Skin Scoring”)
Type of group:
Observational group
Description:
In neonatal participants, skin compatibility of the
Sponsors
Universitätsklinikum Münster, Klinik für Kinder- und Jugendmedizin – Allgemeine Pädiatrie
Eligibility
Sex/Gender
All
Age
0 Days to 1 Years
Inclusion criteria
Inclusion criteria: Preterm or term newborn infants Admission to the neonatal intensive care unit at the University Hospital Münster Clinical indication for one of the four study modules (intubation, HFOV, dexamethasone, skin compatibility) Hemodynamic stability at the time of measurement Written informed consent obtained from the parents (both legal guardians if required)
Exclusion criteria
Exclusion criteria: Severe hemodynamic instability Skin defects or significant irritation in the chest area Congenital malformations affecting lung development or ventilation (e.g., diaphragmatic hernia) Metal implants in the thoracic region (e.g., pacemaker, thoracic wires) Contraindications to the use of EIT No parental consent obtained
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Feasibility, sensitivity, and specificity of Electrical Impedance Tomography (EIT) in neonatal intensive care applications. For each clinical scenario (skin compatibility, endotracheal tube positioning, HFNC, and HFOV optimization), complete EIT data sets on amplitude, phase, and frequency responses will be generated and compared with standard clinical parameters. The objective is a quantitative analysis of relationships between EIT-derived ventilation metrics and physiological responses, and the generation of regional ventilation maps for real-time lung monitoring. Time points of measurement: during each respective clinical application (skin scoring continuously; ETT/HFNC/HFOV before, during, and after intervention). | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement of clinical decision-making based on real-time EIT feedback (e.g., tube positioning, HFNC and HFOV adjustments). Reduction of radiation exposure by potentially decreasing the number of chest X-rays. Correlation of EIT-derived parameters (amplitude, phase, frequency) with standard clinical measures (e.g., ventilator settings, flow, oxygen saturation, blood gas analysis). Assessment of skin compatibility of EIT electrodes (changes in the Neonatal Skin Condition Score over time). Therapeutic influence and clinical impact of EIT parameters on ventilation management (e.g., PEEP or flow adjustments). Feasibility of EIT monitoring across different neonatal ventilation modes (non-invasive and invasive). Time points of measurement: parallel to the respective clinical application (HFNC, HFOV, intubation, electrode use). | — |
Countries
Germany
Contacts
Public ContactAlexander Humberg
Universitätsklinikum Münster, Klinik für Kinder- und Jugendmedizin - Allgemeine Pädiatrie
Outcome results
None listed