C78.7
Conditions
Sponsors
Universitätsklinikum Augsburg
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - previously untreated liver metastasis from colorectal cancer with indication for a hemihepatectomy - size of the metastasis to be resected = 1,5 cm - ability to understand the protocol and give informed consent
Exclusion criteria
Exclusion criteria: - medical or psychological impairments or legal restrictions resulting in reduced capability to give informed consent - lack of any of the listed inclusion criteria - if the pathologist determines, that the integrity of the vascular system of the resected tissue has been compromised (e.g. through surgery or intraoperative biopsy for rapid histopathological workup) rendering perfusion impossible, the patient will be excluded - if histopathological workup after the library perfusion will unexpectedly yield a diagnosis other than the expected cancer entity, the patient will be excluded from the trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Feasibility of the procedure to identify specific vector capsid-displayed peptides targeting human liver metastasis ex vivo. | — |
Secondary
| Measure | Time frame |
|---|---|
| Identification of vector-displayed peptides targeting human liver metastasis ex vivo. | — |
Countries
Germany
Contacts
Public ContactMartin Trepel
Universitätsklinikum Augsburg
Outcome results
None listed