Time course of cerebral hyperperfusion after successful recanalization in ischemic stroke with large vessel occlusion

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00036712

Enrollment

Registered

2026-01-29

Start date

2025-10-28

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I63.9

Interventions

Group 1: Transcranial duplex sonography of the middle cerebral artery on both sides within 6 hours after thrombectomy (TICI 2b-3) and daily on days 2-5 after recanalization

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Mechanical recanalization = TICI 2b (with or without stent)

Exclusion criteria

Exclusion criteria: i. Technically induced vascular injury (dissection, perforation, vascular rupture) ii. Previously known or newly diagnosed, non-acutely treated, significant stenosis of the common carotid artery, ipsilateral or contralateral to the occlusion, internal carotid artery (distal stenosis grade according to NASCET > 50%) or middle cerebral artery in the M1 segment. iii. Lack of transtemporal acoustic window in routine TCD for imaging of the middle cerebral artery in the M1 segme

Design outcomes

Primary

Measure	Time frame
Time required for normalization in cases of relevant differences in transcranial duplex sonography	—

Secondary

Measure	Time frame
mRS at 90 days	—

Countries

Germany

Contacts

Public ContactWolf-Dirk Niesen

Klinik für Neurologie und Neurophysiologie, Universiätsklinikum Freiburg

wolf-dirk.niesen@uniklinik-freiburg.de076127050010

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 7, 2026