Basalcellcarcinom of the facial skin
Conditions
Interventions
Group 1: In patients with an increased risk of developing basal cell carcinoma (see inclusion criteria), an examination of the entire facial skin with line-field confocal optical coherence tomography
Sponsors
Uniklinikum Erlangen, Hautklinik
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Written informed consent to the study - Presence of at least two of the following risk factors for basal cell carcinoma: -- Age = 65 years -- Skin type I or II according to Fitzpatrick scale -- Diagnosis of basal cell carcinoma in the past -- Chronic exposure to sunlight --- of at least 20 years in the context of professional activity or --- of at least 30 years in the context of leisure activities -- Diagnosis of a genetic syndrome with an increased risk of developing basal cell carcinoma (Gorlin-Goltz syndrome, Bazex-Dupré-Christol syndrome, Rombo syndrome) -- Condition after radiotherapy in the head/neck area
Exclusion criteria
Exclusion criteria: - Insufficient cognitive capacity to consent to the study - Presence of a skin disease in the examination area which significantly restricts the examination conditions (e.g. but not limited to extensive nevus flammeus, acne conglobata) in the opinion of the investigator - Disease or condition that makes examination with LC-OCT impossible - Previous participation in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Relative number of subclinical basal cell carcinomas (number of subclinical basal cell carcinomas per patient examined) diagnosed and histologically verified by LC-OCT examination | — |
Secondary
| Measure | Time frame |
|---|---|
| Relative number of false positive findings (number of sample biopsies that are performed on the basis of a diagnosis of basal cell carcinoma using LC-OCT and cannot be confirmed histologically) | — |
Countries
Germany
Contacts
Public ContactCarola Berking
Uniklinikum Erlangen, Hautklinik
Outcome results
None listed