Adult patients (18 years or older) undergoing elective cardiac surgery for whom TEE is indicated pre- and postoperatively.
Conditions
Interventions
Group 1: Adult patients (18 years or older) undergoing elective cardiac surgery with indication of pre- and postoperative TEE.
This prospective observational study compares the individually measured
Sponsors
Universitätsklinikum Bonn, Klinik und Poliklinik für Anästhesiologie und Operative Intensivmedizin
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients must undergo elective cardiac surgery using heart lung machine; Indication of TEE and uncalibrated pulse contour analysis.
Exclusion criteria
Exclusion criteria: Contraindication of TEE and uncalibrated pulse contour analysis; Arrhythmia influencing measurement precision.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary endpoint is the difference between the individually measured cardiac output (CO) after induction of anesthesia (assessed via TEE and/or pulse contour analysis) and the standardized CO of 2.4 l/min/m² body surface area during cardiopulmonary bypass (CPB), calculated using the Du Bois and Du Bois formula. | — |
Secondary
| Measure | Time frame |
|---|---|
| Recording and analysis of regional cerebral oxygen saturation (rSO2) using near-infrared spectroscopy (NIRS) before and during cardiopulmonary bypass (CPB). Comparison of cardiac output (CO) values obtained via transesophageal echocardiography (TEE) and uncalibrated pulse contour analysis. | — |
Countries
Germany
Contacts
Public ContactMarcus Thudium
Universitätsklinikum Bonn, Klinik und Poliklinik für Anästhesiologie und Operative Intensivmedizin
Outcome results
None listed