Evaluation of the efficacy and safety of intraoperative MRI in the surgery of brain metastases

Evaluation of the efficacy and safety of intraoperative MRI in the surgery of brain metastases - MET-MRI

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00036664

Enrollment

154

Registered

2025-04-28

Start date

2025-05-01

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C79.4

Interventions

Group 1: In this study, we will conduct surgical resections of brain metastases using intraoperative MRI (ioMRI) to enhance surgical precision. The interventions include pre-operative assessment, surg

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with diagnosed brain metastases for whom surgical resection is indicated.

Exclusion criteria

Exclusion criteria: Patient's incapacity to enter the MRI

Design outcomes

Primary

Measure	Time frame
The proportion of patients in whom a complete cytoreduction of brain metastases is achieved with the aid of intraoperative MRI is confirmed by a postoperative MRI within 72 hours of the operation.	—

Secondary

Measure	Time frame
Clinical outcomes (functional status, persistent neurological deficits, new neurological deterioration, survival rates), surgical complications (including wound infections), anaesthesiological complications, length of hospital stay, duration of surgery and intraoperative adjustments based on iMRI, image-physiological parameters (haemorrhage, ischaemia, oedema, identification of remaining tumour parts, cerebrospinal fluid). hospital stay, duration of surgery and intraoperative adjustments based on iMRI findings, image morphological parameters (haemorrhage, ischaemia, oedema, identification of remaining tumour parts, cerebrospinal fluid accumulation, structural brain tissue changes).	—

Measure

Time frame

Clinical outcomes (functional status, persistent neurological deficits, new neurological deterioration, survival rates), surgical complications (including wound infections), anaesthesiological complications, length of hospital stay, duration of surgery and intraoperative adjustments based on iMRI, image-physiological parameters (haemorrhage, ischaemia, oedema, identification of remaining tumour parts, cerebrospinal fluid). hospital stay, duration of surgery and intraoperative adjustments based on iMRI findings, image morphological parameters (haemorrhage, ischaemia, oedema, identification of remaining tumour parts, cerebrospinal fluid accumulation, structural brain tissue changes).

—

Countries

Germany

Contacts

Public ContactMaria Goldberg

Klinik und Poliklinik für Neurochirurgie

maria.goldberg@tum.de+4941402151

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 11, 2026