K72.7
Conditions
Interventions
Group 1: hourly cutaneous patch based mesurement of K+, Na2+ and temperature
+ continuous UWB based motion analysis
+ regular blood sampling (3x/week)
+ daily clinical hepatic enzaphalopathy assessme
Sponsors
Else-Kröner-Fresenius-Zentrum
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: patients hospitalized on the MK1-S4 ward in UKDD with increased HE risk: Age >18, Informed Consent possible Confirmed liver cirrhosis or Portosystemic shunt (TIPS, traumatic, portal vein thrombosis/compression) or Acute liver failure
Exclusion criteria
Exclusion criteria: Not capable of giving informed consent and no authorized representative No knowledge of the German or English language Severe cognitive impairment of a different origin Patch allergy or extensive skin damage/infection Diseases with impairment of the sweat glands (cystic fibrosis/Sjögren's/scleroderma) Known hyperhidrosis Photosensitive epilepsy Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prediction of HE episodes based on motion patterns derived from UWB motion analysis | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation of the measured electrolytes with standard venous blood draw laboratory analysis | — |
Countries
Germany
Contacts
Public ContactMagdalena Wekenborg
Else Kröner Fresenius Zentrum für Digitale Gesundheit
Outcome results
None listed